{"id":12767,"date":"2022-05-12T12:41:16","date_gmt":"2022-05-12T10:41:16","guid":{"rendered":"https:\/\/www.famelab.gr\/?p=12767"},"modified":"2025-10-30T07:46:56","modified_gmt":"2025-10-30T07:46:56","slug":"effects-of-exercise-and-physical-activity-levels-on-vaccination-efficacy-a-systematic-review-and-meta-analysis-2","status":"publish","type":"post","link":"https:\/\/famelab.gr\/el\/effects-of-exercise-and-physical-activity-levels-on-vaccination-efficacy-a-systematic-review-and-meta-analysis-2\/","title":{"rendered":"Effects of Exercise and Physical Activity Levels on Vaccination Efficacy: A Systematic Review and Meta-Analysis"},"content":{"rendered":"

\"EffectsDinas PC, Koutedakis Y, Ioannou LG, Metsios G, Kitas GD. Effects of Exercise and Physical Activity Levels on Vaccination Efficacy: A Systematic Review and Meta-Analysis. Vaccines (Basel). 2022 May 12;10(5):769. doi: 10.3390\/vaccines10050769. PMID: 35632525; PMCID: PMC9146578.<\/span><\/p>\n

Abstract:<\/span><\/strong><\/p>\n

Objective:\u00a0We examined whether different intensities of exercise and\/or physical activity (PA) levels affected and\/or associated with vaccination efficacy.<\/p>\n

Methods:A systematic review and meta-analysis was conducted and registered with PROSPERO (CRD42021230108). The PubMed, EMBASE, Cochrane Library (trials), SportDiscus, and CINAHL databases were searched up to January 2022.<\/p>\n

Results:\u00a0In total, 38 eligible studies were included. Chronic exercise increased influenza antibodies (standardized mean difference (SMD) = 0.49, confidence interval (CI) = 0.25-0.73, Z = 3.95, I2<\/sup>\u00a0= 90%,\u00a0p<\/i>\u00a0&lt; 0.01), which was mainly driven by aerobic exercise (SMD = 0.39, CI = 0.19-0.58, Z = 3.96, I2<\/sup>\u00a0= 77%,\u00a0p<\/i>\u00a0&lt; 0.01) as opposed to combined (aerobic + resistance;\u00a0p<\/i>\u00a0= 0.07) or other exercise types (i.e., taiji and qigong, unspecified;\u00a0p<\/i>\u00a0&gt; 0.05). PA levels positively affected antibodies in response to influenza vaccination (SMD = 0.18, CI = 0.02-0.34, Z = 2.21, I2<\/sup>\u00a0= 76%,\u00a0p<\/i>\u00a0= 0.03), which was mainly driven by high PA levels compared to moderate PA levels (Chi2<\/sup>\u00a0= 10.35, I2<\/sup>\u00a0= 90.3%,\u00a0p<\/i>\u00a0&lt; 0.01). Physically active individuals developed influenza antibodies in response to vaccination in &gt;4 weeks (SMD = 0.64, CI = 0.30-0.98, Z = 3.72, I2<\/sup>\u00a0= 83%,\u00a0p<\/i>\u00a0&lt; 0.01) as opposed to &lt;4 weeks (p<\/i>\u00a0&gt; 0.05; Chi2 = 13.40, I2<\/sup>\u00a0= 92.5%,\u00a0p<\/i>\u00a0&lt; 0.01) post vaccination.<\/p>\n

Conclusion:\u00a0Chronic aerobic exercise or high PA levels increased influenza antibodies in humans more than vaccinated individuals with no participation in exercise\/PA. The evidence regarding the effects of exercise\/PA levels on antibodies in response to vaccines other than influenza is extremely limited.<\/p>\n

Full Text Link:<\/span><\/strong><\/p>\n

https:\/\/pubmed.ncbi.nlm.nih.gov\/35632525\/<\/a><\/p>\n

\"\"<\/p>\n

 <\/p>\n

 <\/p>","protected":false},"excerpt":{"rendered":"

Dinas PC, Koutedakis Y, Ioannou LG, Metsios G, Kitas GD. Effects of Exercise and Physical Activity Levels on Vaccination Efficacy: A Systematic Review and Meta-Analysis. Vaccines (Basel). 2022 May 12;10(5):769. doi: 10.3390\/vaccines10050769. PMID: 35632525; PMCID: PMC9146578. Abstract: Objective:\u00a0We examined whether different intensities of exercise and\/or physical activity (PA) levels affected and\/or associated with vaccination efficacy. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-12767","post","type-post","status-publish","format-standard","hentry","category-fame-lab-publications-2022"],"_links":{"self":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/12767","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/comments?post=12767"}],"version-history":[{"count":1,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/12767\/revisions"}],"predecessor-version":[{"id":16536,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/12767\/revisions\/16536"}],"wp:attachment":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/media?parent=12767"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/categories?post=12767"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/tags?post=12767"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}