{"id":5891,"date":"2017-07-05T09:39:55","date_gmt":"2017-07-05T07:39:55","guid":{"rendered":"https:\/\/www.famelab.gr\/?p=5891"},"modified":"2025-10-30T08:19:02","modified_gmt":"2025-10-30T08:19:02","slug":"browning-formation-markers-of-subcutaneous-adipose-tissue-in-relation-to-resting-energy-expenditure-physical-activity-and-diet-in-humans","status":"publish","type":"post","link":"https:\/\/famelab.gr\/el\/browning-formation-markers-of-subcutaneous-adipose-tissue-in-relation-to-resting-energy-expenditure-physical-activity-and-diet-in-humans\/","title":{"rendered":"Browning formation markers of subcutaneous adipose tissue in relation to resting energy expenditure, physical activity and diet in humans"},"content":{"rendered":"

\"FAME<\/a>Dinas PC<\/a>, Valente A<\/a>, Granzotto M, Rossato M, Vettor R, Zacharopoulou A, Carrillo AE<\/a>, Davies NA, Gkiata P<\/a>, Jamurtas AZ, Koutedakis Y, Metsios GS, Flouris AD<\/a>. Browning formation markers of subcutaneous adipose tissue in relation to resting energy expenditure, physical activity and diet in humans. Horm Mol Biol Clin Investig. 2017 Jul 5;31(1):\/j\/hmbci.2017.31.issue-1\/hmbci-2017-0008\/hmbci-2017-0008.xml. doi: 10.1515\/hmbci-2017-0008. PMID: 28678735.<\/span><\/p>\n

Abstract:<\/strong><\/span><\/p>\n

Background: Regular exercise and diet may contribute to white adipose tissue (WAT) conversion into a brown adipose-like phenotype that may increase resting energy expenditure (REE), leading to weight loss. We examined the relationship between REE, physical activity (PA) participation and diet with browning formation markers of subcutaneous WAT in healthy men. Materials and methods We assessed REE, diet and body composition of 32 healthy men [age (years): 36.06 \u00b1 7.36, body mass index (BMI): 27.06 \u00b1 4.62 (kg\/m2)]. Participants also underwent measurements of PA [metabolic equivalent (MET)-min\/week] using the International Physical Activity Questionnaire (IPAQ), while they undertook a subcutaneous fat biopsy from the abdominal region to assess the mRNA expressions of uncoupling protein 1 (UCP1), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1\u03b1), peroxisome proliferator-activated receptor alpha (PPAR\u03b1) and peroxisome proliferator-activated receptor gamma (PPAR\u03b3).<\/p>\n

Results: We found no associations between the UCP1, PGC-1\u03b1, PPAR\u03b1 and PPAR\u03b3 mRNAs with REE, PA levels and diet (p > 0.05). However, the PGC-1\u03b1, PPAR\u03b1 and PPAR\u03b3 mRNAs were more expressed in individuals displaying moderate rather than low PA levels (p < 0.05). Furthermore, PGC-1\u03b1, PPAR\u03b1 and PPAR\u03b3 mRNAs were negatively correlated with fat mass percentage (p < 0.05). PGC-1\u03b1 and PPAR\u03b1 mRNAs were also negatively correlated with BMI, while PGC-1\u03b1 mRNA was inversely associated with waist-to-hip ratio (p < 0.05).<\/p>\n

Conclusion: REE, PA levels and diet are not associated with browning formation indices of subcutaneous adipose tissue in healthy adult men.<\/p>\n

Full Text Link<\/strong><\/span>:<\/p>\n

https:\/\/pubmed.ncbi.nlm.nih.gov\/28678735\/<\/a><\/p>\n

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 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Dinas PC, Valente A, Granzotto M, Rossato M, Vettor R, Zacharopoulou A, Carrillo AE, Davies NA, Gkiata P, Jamurtas AZ, Koutedakis Y, Metsios GS, Flouris AD. Browning formation markers of subcutaneous adipose tissue in relation to resting energy expenditure, physical activity and diet in humans. Horm Mol Biol Clin Investig. 2017 Jul 5;31(1):\/j\/hmbci.2017.31.issue-1\/hmbci-2017-0008\/hmbci-2017-0008.xml. doi: 10.1515\/hmbci-2017-0008. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-5891","post","type-post","status-publish","format-standard","hentry","category-fame-lab-publications-2017"],"_links":{"self":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/5891","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/comments?post=5891"}],"version-history":[{"count":1,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/5891\/revisions"}],"predecessor-version":[{"id":16599,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/5891\/revisions\/16599"}],"wp:attachment":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/media?parent=5891"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/categories?post=5891"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/tags?post=5891"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}