{"id":6777,"date":"2013-01-30T14:40:33","date_gmt":"2013-01-30T12:40:33","guid":{"rendered":"https:\/\/www.famelab.gr\/?p=6777"},"modified":"2025-10-30T09:00:35","modified_gmt":"2025-10-30T09:00:35","slug":"acute-impact-of-active-and-passive-electronic-cigarette-smoking-on-serum-cotinine-and-lung-function","status":"publish","type":"post","link":"https:\/\/famelab.gr\/el\/acute-impact-of-active-and-passive-electronic-cigarette-smoking-on-serum-cotinine-and-lung-function\/","title":{"rendered":"Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function"},"content":{"rendered":"<p><span style=\"color: #000000;\"> <img decoding=\"async\" class=\"size-full wp-image-6778 alignright\" src=\"https:\/\/www.famelab.gr\/wp-content\/uploads\/2022\/03\/Inhalation-Toxicology.png\" alt=\"Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function\" width=\"167\" height=\"167\" \/><a href=\"https:\/\/famelab.gr\/el\/people\/\" target=\"_blank\" rel=\"noopener noreferrer\">Flouris AD<\/a>, <a href=\"https:\/\/famelab.gr\/el\/alumni\/\" target=\"_blank\" rel=\"noopener noreferrer\">Chorti MS<\/a>, <a href=\"https:\/\/famelab.gr\/el\/alumni\/\" target=\"_blank\" rel=\"noopener noreferrer\">Poulianiti KP<\/a>, Jamurtas AZ, Kostikas K, Tzatzarakis MN, Wallace Hayes A, Tsatsakis AM, Koutedakis Y. Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function. Inhal Toxicol. 2013 Feb;25(2):91-101. doi: 10.3109\/08958378.2012.758197. PMID: 23363041.<\/span><\/p>\n<p><span style=\"color: #000000;\"><strong>Abstract:<\/strong><\/span><\/p>\n<p>Context: Electronic cigarettes (e-cigarettes) are becoming increasingly popular yet their effects on health remain unknown.<\/p>\n<p>Objective: To conduct the first comprehensive and standardized assessment of the acute impact of active and passive e-cigarette smoking on serum cotinine and lung function, as compared to active and passive tobacco cigarette smoking.<\/p>\n<p>Materials and methods: Fifteen smokers (\u226515 cigarettes\/day; seven females; eight males) and 15 never-smokers (seven females; eight males) completed this repeated-measures controlled study. Smokers underwent a control session, an active tobacco cigarette (their favorite brand) smoking session and an active e-cigarette smoking session. Never-smokers underwent a control session, a passive tobacco cigarette smoking session and a passive e-cigarette smoking session. Serum cotinine, lung function, exhaled carbon monoxide and nitric oxide were assessed. The level of significance was set at p \u2264 0.001 to adjust for multiple comparisons.<\/p>\n<p>Results: e-Cigarettes and tobacco cigarettes generated similar (p &gt; 0.001) effects on serum cotinine levels after active (60.6 \u00b1 34.3 versus 61.3 \u00b1 36.6 ng\/ml) and passive (2.4 \u00b1 0.9 versus 2.6 \u00b1 0.6 ng\/ml) smoking. Neither a brief session of active e-cigarette smoking (indicative: 3% reduction in FEV1\/FVC) nor a 1 h passive e-cigarette smoking (indicative: 2.3% reduction in FEV1\/FVC) significantly affected the lung function (p &gt; 0.001). In contrast, active (indicative: 7.2% reduction in FEV1\/FVC; p &lt; 0.001) but not passive (indicative: 3.4% reduction in FEV1\/FVC; p = 0.005) tobacco cigarette smoking undermined lung function.<\/p>\n<p>Conclusion: Regarding short-term usage, the studied e-cigarettes generate smaller changes in lung function but similar nicotinergic impact to tobacco cigarettes. Future research should target the health effects of long-term e-cigarette usage, including the effects of nicotine dosage.<\/p>\n<p><span style=\"color: #000000;\"><strong>Full Text Link: <\/strong><\/span><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23363041\/\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/pubmed.ncbi.nlm.nih.gov\/23363041\/<\/a><\/p>\n<p><img decoding=\"async\" class=\"alignnone wp-image-8302 size-full\" src=\"https:\/\/www.famelab.gr\/wp-content\/uploads\/2021\/11\/Line.png\" alt=\"\" width=\"1316\" height=\"1\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>Flouris AD, Chorti MS, Poulianiti KP, Jamurtas AZ, Kostikas K, Tzatzarakis MN, Wallace Hayes A, Tsatsakis AM, Koutedakis Y. Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function. Inhal Toxicol. 2013 Feb;25(2):91-101. doi: 10.3109\/08958378.2012.758197. PMID: 23363041. Abstract: Context: Electronic cigarettes (e-cigarettes) are becoming increasingly popular yet their effects on [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[],"class_list":["post-6777","post","type-post","status-publish","format-standard","hentry","category-fame-lab-publications-2013"],"_links":{"self":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/6777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/comments?post=6777"}],"version-history":[{"count":1,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/6777\/revisions"}],"predecessor-version":[{"id":16655,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/6777\/revisions\/16655"}],"wp:attachment":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/media?parent=6777"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/categories?post=6777"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/tags?post=6777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}