{"id":6797,"date":"2012-02-15T14:56:45","date_gmt":"2012-02-15T12:56:45","guid":{"rendered":"https:\/\/www.famelab.gr\/?p=6797"},"modified":"2025-10-30T09:02:45","modified_gmt":"2025-10-30T09:02:45","slug":"respiratory-and-immune-response-to-maximal-physical-exertion-following-exposure-to-secondhand-smoke-in-healthy-adults","status":"publish","type":"post","link":"https:\/\/famelab.gr\/el\/respiratory-and-immune-response-to-maximal-physical-exertion-following-exposure-to-secondhand-smoke-in-healthy-adults\/","title":{"rendered":"Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults"},"content":{"rendered":"

\"FAME<\/a>Flouris AD<\/a>, Metsios GS, Carrillo AE<\/a>, Jamurtas AZ, Stivaktakis PD, Tzatzarakis MN, Tsatsakis AM, Koutedakis Y. Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults. PLoS One. 2012;7(2):e31880. doi: 10.1371\/journal.pone.0031880. Epub 2012 Feb 15. Erratum in: PLoS One. 20127(4): doi\/10.1371\/annotation\/f2eb18a5-4dd2-49c1-95e9-2299402ee5a6. Carrill, Andres E [corrected to Carrillo, Andres E]. PMID: 22355401; PMCID: PMC3280209.<\/span><\/p>\n

Abstract:<\/strong><\/span><\/p>\n

We assessed the cardiorespiratory and immune response to physical exertion following secondhand smoke (SHS) exposure through a randomized crossover experiment. Data were obtained from 16 (8 women) non-smoking adults during and following a maximal oxygen uptake cycling protocol administered at baseline and at 0-, 1-, and 3- hours following 1-hour of SHS set at bar\/restaurant carbon monoxide levels. We found that SHS was associated with a 12% decrease in maximum power output, an 8.2% reduction in maximal oxygen consumption, a 6% increase in perceived exertion, and a 6.7% decrease in time to exhaustion (P<0.05).<\/p>\n

Moreover, at 0-hours almost all respiratory and immune variables measured were adversely affected (P<0.05). For instance, FEV(1) values at 0-hours dropped by 17.4%, while TNF-\u03b1 increased by 90.1% (P<0.05). At 3-hours mean values of cotinine, perceived exertion and recovery systolic blood pressure in both sexes, IL4, TNF-\u03b1 and IFN-\u03b3 in men, as well as FEV(1)\/FVC, percent predicted FEV(1), respiratory rate, and tidal volume in women remained different compared to baseline (P<0.05). It is concluded that a 1-hour of SHS at bar\/restaurant levels adversely affects the cardiorespiratory and immune response to maximal physical exertion in healthy nonsmokers for at least three hours following SHS.<\/p>\n

Full Text Link: <\/strong><\/span><\/p>\n

https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0031880<\/a><\/p>\n

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https:\/\/www.famelab.gr\/wp-content\/uploads\/2022\/04\/Respiratory-and-immune-response-to-maximal-physical-exertion-following-exposure-to-secondhand-smoke-in-healthy-adults_2012.pdf<\/a><\/p>\n

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 <\/p>\n","protected":false},"excerpt":{"rendered":"

Flouris AD, Metsios GS, Carrillo AE, Jamurtas AZ, Stivaktakis PD, Tzatzarakis MN, Tsatsakis AM, Koutedakis Y. Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults. PLoS One. 2012;7(2):e31880. doi: 10.1371\/journal.pone.0031880. Epub 2012 Feb 15. Erratum in: PLoS One. 20127(4): doi\/10.1371\/annotation\/f2eb18a5-4dd2-49c1-95e9-2299402ee5a6. Carrill, Andres E [corrected to Carrillo, Andres E]. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-6797","post","type-post","status-publish","format-standard","hentry","category-fame-lab-publications-2012"],"_links":{"self":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/6797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/comments?post=6797"}],"version-history":[{"count":1,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/6797\/revisions"}],"predecessor-version":[{"id":16658,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/posts\/6797\/revisions\/16658"}],"wp:attachment":[{"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/media?parent=6797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/categories?post=6797"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/famelab.gr\/el\/wp-json\/wp\/v2\/tags?post=6797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}