Dr. Lydia Tsoutsoubi is a cardiovascular and environmental physiologist specializing in human thermoregulation and cardiovascular responses to environmental stress. Her research focuses on human responses and adaptations to heat and cold stress across occupational, environmental, and space settings.
Dr. Lydia Tsoutsoubi earned her BSc in Physical Education and Sport Science, MSc in Exercise and Health, and PhD in Environmental Physiology from the University of Thessaly, Greece. Her doctoral research focused on the thermoregulatory role of the vasomotion system and the mechanisms regulating human responses to thermal stress in healthy and clinical populations. She further specialized in environmental physiology through academic training at the University of Porto, Portugal.
Her research focuses on the interactions between thermoregulation, cardiovascular function, and environmental stress, with particular emphasis on heat and cold exposure, cutaneous circulation, and human adaptation to extreme environments. As a Researcher at the Jožef Stefan Institute, Slovenia, she contributes to projects in environmental and space physiology, including studies supported by the European Space Agency (ESA).
Dr. Tsoutsoubi has participated in several European and internationally funded research projects and has collaborated with organizations such as the International Labour Organization (ILO). At FAME Lab, she serves as a Senior Researcher, investigating how thermal stress, environmental challenges, and climate change influence thermoregulation, cardiovascular function, and human health. Her work has been published in leading international journals and contributes to advancing our understanding of human physiological adaptation to a changing environment.
Tsoutsoubi L., Ioannou L.G., Ciuha U., Fisher J.T., Possnig C., Simpson L.L., Flouris A.D., Lawley J., Mekjavic I.B. (2024). Validation of formulae predicting stroke volume from arterial pressure: with particular emphasis on upright individuals in hot ambient conditions. Frontiers in Physiology.
Tsoutsoubi L., Ioannou L.G., Billie A.K., Cheung S.S., Daanen H.A., Mekjavic I.B., Flouris A.D. (2023). Central versus peripheral mechanisms of cold-induced vasodilation: a study in the fingers and toes of people with paraplegia. European Journal of Applied Physiology.
Tsoutsoubi L., Ioannou L.G., Mantzios K., Ziaka S., Nybo L., Flouris A.D. (2022). Cardiovascular Stress and Characteristics of Cold-Induced Vasodilation in Women and Men during Cold-Water Immersion: A Randomized Control Study. Biology.
Tsoutsoubi L., Ioannou L.G., Flouris A.D. (2021). Mortality due to circulatory causes in hot and cold environments in Greece. Scandinavian Cardiovascular Journal.
Tsoutsoubi L., Ioannou L.G., Cheung S.S., Flouris A.D. (2021). Influence of core temperature changes during whole-body warming and cooling on cutaneous vascular reactivity. Journal of Human Performance in Extreme Environments.
Ioannou L.G., Mantzios K., Tsoutsoubi L., Notley S.R., Dinas P.C., Brearley M., Epstein Y., Havenith G., Sawka M.N., Broede P., Mekjavic I.B., Kenny G.P., Bernard T.E., Nybo L., Flouris A.D. (2022). Indicators to assess physiological heat strain – Part 1: Systematic review. Temperature.
Ioannou L.G., Tsoutsoubi L., Mantzios K., Vliora M., Nintou E., Piil J.F., Notley S.R., Dinas P.C., Gourzoulidis G.A., Havenith G., Brearley M., Mekjavic I.B., Kenny G.P., Nybo L., Flouris A.D. (2022). Indicators to assess physiological heat strain – Part 3: Multi-country field evaluation and consensus recommendations. Temperature.
Ioannou L.G., Mantzios K., Tsoutsoubi L., Nintou E., Vliora M., Gkiata P., Dallas C.N., Gkikas G., Agaliotis G., Sfakianakis K., Kapnia A.K., Testa D.T., Amorim T., Dinas P.C., Mayor T.S., Gao C., Nybo L., Flouris A.D. (2021). Occupational heat stress: multi-country evidence and interventions. International Journal of Environmental Research and Public Health.
Ioannou L.G., Tsoutsoubi L., Mantzios K., Gkikas G., Agaliotis G., Koutedakis Y., Garcia-Leon D., Havenith G., Liang J., Arkolakis C., Glaser J., Kenny G.P., Mekjavic I.B., Nybo L., Flouris A.D. (2024). The impact of workplace heat and cold on work time loss. Journal of Occupational and Environmental Medicine.
Ana Bonell, Asma Abdul Malik Qureshi, Andreas D Flouris, Lydia Tsoutsoubi, Amanda N Sferruzzi-Perri, Jai K Das, Jane E Hirst, Leonidas G Ioannou (2026). Physiological and biological response to heat exposure in pregnancy: a systematic review and meta-analysis. The Lancet Planetary Health.
