We assess human and equipment performance both in the laboratory and in real-world conditions at altitude, wind, cold, and humidity in the Highlands of Scotland, the Alps, and the Himalayas. We conduct hypoxic training for athletes, prepare mountaineers for expeditions, and provide medical support for illnesses and accidents related to high altitude.With our state-of-the-art environmental chamber and the pioneering methods we have developed, we study how the human body adapts to any environment on the planet. We evaluate fabrics, clothing, and equipment under different conditions, contributing to the design and production of better products.