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KONSTANTINOS MANTZIOS

Role

Dr. Konstantinos Mantzios is an environmental physiologist and software developer specializing in human-computer interaction, big data, and machine learning. Ηe develops innovative technologies, with a current focus on heat stress management and enhancing human well-being through advanced, data-driven solutions. 

Dr. Konstantinos Mantzios is an environmental physiologist and software developer specializing in human-computer interaction and advanced technological solutions for human health. He focuses on the integration of environmental physiology, occupational health, and data-driven technology to address the challenges of heat stress, climate resilience, and human performance. His research combines experimental physiology with predictive modeling and machine learning, developing tools to forecast thermal strain and productivity loss under climate change scenarios. He has led the creation of mobile and web-based applications for real-time monitoring of physiological and environmental data, integrating wearables, sensors, and cloud infrastructures into practical solutions for workers and athletes. 

After completing his studies in Sport Science at the University of Thessaly, Dr. Konstantinos Mantzios pursued an MSc in Exercise and Health and went on to earn his Ph.D. in Environmental Physiology, focusing on technological applications for human health and performance. His doctoral research centered on predictive heat strain models and innovative methods to monitor thermal stress in occupational and athletic settings. He has been actively involved in numerous European and international research projects, on occupational heat stress. His work bridges physiology, data science, and technology, leveraging machine learning, climate data, and real-time monitoring systems to translate complex research into practical solutions for human well-being. 

Beyond research, Dr. Mantzios has extensive experience in developing mobile and web applications for health monitoring. He has designed platforms signal tracking and processing, heat stress assessment tools, and wearable data integration, employing tools such as Flutter, Python, PHP, and cloud-based infrastructures. Currently, Dr. Mantzios continues his research as a postdoctoral fellow at FAME Lab (University of Thessaly), while also collaborating with partners to craft technological solutions that address pressing challenges in

  1. Mantzios K., Ioannou L.G., Panagiotaki Z., Ziaka S., Periard P.D., Racinais S., Nybo L., Flouris A.D. (2021). Effects of weather parameters on endurance running performance: discipline specific analysis of 1258 races. Medicine & Science in Sports & Exercise. DOI: 10.1249/MSS.0000000000002769.
  2. Mantzios K., Ioannou L.G, Nikolaki E., Gkiata P., Harahousou G., Tsoutsoubi L., Dinas P.C., Flouris A.D. (2024). Validation of Core, Rectal and Skin Temperature Predictions of a Free Web-Based Predictive Heat Strain Software Based on the ISO 7933:2023 Standard in Recreational Athletes. Journal of Science in Sport and Exercise. DOI: 10.1007/s42978-024-00309-5.
  3. Mantzios, K., Pappas, A., Tsianos, G.-I., Flouris, A.D. Night-Time Heart Rate Variability during an Expedition to Mt Everest: A Case Report. Sports 2023, 11, 48. https://doi.org/10.3390/sports11020048 
  4. Ioannou L.G., Tsoutsoubi L., Mantzios K., Notley S.R., Dinas P.C., Brearley M., Epstein Y., Havenith G., Sawka M.N., Broede P., Mekjavic I.B., Kenny G.P., Bernard T.E., Nybo L., Flouris A.D. (2022). Indicators to assess physiological heat strain – Part 1: Systematic review. Temperature. DOI: 10.1080/23328940.2022.2037376.
  5. Ioannou L.G., Tsoutsoubi L., Mantzios K., Vliora M., Nintou E., Piil J.F., Notley S.R., Dinas P.C., Gourzoulidis G.A., Havenith G., Brearley M., Mekjavic I.B., Kenny G.P., Nybo L., Flouris A.D. (2022). Indicators to assess physiological heat strain – Part 3: Multi-country field evaluation and consensus recommendations. Temperature. DOI: 10.1080/23328940.2022.2044739.
  6. Ioannou L.G., Mantzios K., Tsoutsoubi L., Panagiotaki Z., Kapnia A., Ciuha U., Nybo L., Flouris A.D., Mekjavic I.B. (2021). Effect of a simulated heat wave on physiological strain and labour productivity. International Journal of Environmental Research and Public Health, 18(6), 3011. DOI: 10.3390/ijerph18063011.
  7. Ioannou L.G., Mantzios K., Tsoutsoubi L., Nintou E., Vliora M., Gkiata P., Dallas C.N., Gkikas G., Agaliotis G., Sfakianakis K., Kapnia A.K., Testa D.T., Amorim T., Dinas P.C., Mayor T.S., Gao C., Nybo L., Flouris A.D. (2021). Occupational heat stress: multi-country evidence and interventions. International Journal of Environmental Research and Public Health, 18(12), 6303. DOI: 10.3390/ijerph18126303.
  8. Leonidas G. Ioannou, Lydia Tsoutsoubi, Konstantinos Mantzios, Georgios Gkikas, Gerasimos Agaliotis, Yiannis Koutedakis, David García-León, George Havenith, Jack Liang, Costas Arkolakis, Jason Glaser, Glen P. Kenny, Igor B. Mekjavic, Lars Nybo, Andreas D. Flouris (2025). The impact of workplace heat and cold on work time loss. Journal of Occupational and Environmental Medicine. DOI: 10.1097/JOM.0000000000003332.
  9. Ioannou L.G., Tsoutsoubi L., Mantzios K., Gkikas G., Piil J.F., Dinas P.C., Notley C.R., Kenny G.P., Nybo L., Flouris A.D. (2021). The impacts of sun exposure on worker physiology and cognition: multi-country evidence and interventions. International Journal of Environmental Research and Public Health, 18(14), 7698. DOI: 10.3390/ijerph18147698.
  10. Tsoutsoubi L., Ioannou L.G., Mantzios K., Ziaka S., Nybo L., Flouris A.D. (2022) Cardiovascular Stress and Characteristics of Cold-Induced Vasodilation in Women and Men during Cold-Water Immersion: A Randomized Control Study. Biology, 11(7), 1054, DOI: 10.3390/biology11071054